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Peptide Encyclopedia
Members: pricing & sourcing →Browse every compound by category. Each entry separates what's established from what's anecdotal, and links to primary literature where it exists.
GLP-1 & Metabolic
Pillar →5-Amino-1MQ
A small-molecule NNMT inhibitor studied in early metabolic research; technically not a peptide, but commonly grouped with metabolic compounds in the community.
AOD-9604
A synthetic fragment of human growth hormone (the 176-191 region) marketed for fat loss, but with disappointing human weight-loss evidence.
Cagrilintide
An investigational long-acting amylin analog studied for weight management, frequently in combination with semaglutide (the CagriSema combination).
Liraglutide
An FDA-approved GLP-1 receptor agonist — the daily-injection predecessor to weekly agents like semaglutide — with established human trial data.
Mazdutide
An investigational dual GLP-1 and glucagon receptor agonist studied for weight management and metabolic outcomes, with a notable trial program in China.
Retatrutide
An investigational triple agonist targeting the GLP-1, GIP and glucagon receptors, notable for unusually large weight reduction in early human trials.
Semaglutide
A GLP-1 receptor agonist with a strong human trial record and multiple FDA approvals for type 2 diabetes and chronic weight management.
Survodutide
An investigational dual GLP-1 and glucagon receptor agonist studied for obesity and metabolic liver disease (MASH/NASH).
Tesofensine
A small-molecule triple monoamine reuptake inhibitor (not a peptide) originally developed for neurological disease and later studied for obesity.
Tirzepatide
A dual GIP and GLP-1 receptor agonist with FDA approvals for type 2 diabetes and chronic weight management, supported by large randomized trials.
Recovery & Healing
Pillar →BPC-157
A synthetic 15–amino-acid peptide derived from a protein found in gastric juice, studied predominantly in animal models for soft-tissue and gastrointestinal healing.
KPV
A three-amino-acid fragment of α-MSH studied for anti-inflammatory activity, particularly in the gut, largely in preclinical models.
Larazotide
An orally-acting peptide that regulates intestinal tight junctions, studied primarily as an adjunct in celiac disease.
Pentadeca Arginate (PDA)
A newer compound structurally related to BPC-157, marketed heavily for tissue recovery — but with a notably thin published evidence base.
TB-500
A synthetic peptide based on an active region of thymosin beta-4, a naturally occurring protein involved in cell migration and tissue repair.
VIP (Vasoactive Intestinal Peptide)
A naturally occurring signaling neuropeptide with broad roles in immune and inflammatory regulation, discussed in chronic-inflammation and gut contexts.
Growth Hormone Secretagogues
Pillar →CJC-1295
A synthetic analog of growth hormone-releasing hormone (GHRH) designed for a longer duration of action, studied for stimulating the body's own GH release.
GHRP-2
A growth-hormone-releasing peptide that stimulates GH via the ghrelin receptor, also increasing appetite.
GHRP-6
An early growth-hormone-releasing peptide acting on the ghrelin receptor, notable for pronounced appetite stimulation.
Hexarelin
A potent growth-hormone-releasing peptide acting on the ghrelin receptor, with additional research interest in cardiac tissue.
IGF-1 LR3
A modified, long-acting analog of insulin-like growth factor 1 used as a research chemical for its anabolic signaling — with meaningful safety concerns.
Ipamorelin
A selective ghrelin-receptor agonist studied as a growth hormone secretagogue — it prompts the pituitary to release the body's own growth hormone.
MK-677
An orally active ghrelin-receptor agonist (growth hormone secretagogue) that raises GH and IGF-1; a small molecule rather than a peptide, with some human study data.
Sermorelin
A GHRH analog (the 1-29 fragment) with a history of approved diagnostic/clinical use, now commonly compounded as a growth hormone secretagogue.
Tesamorelin
A stabilized growth-hormone-releasing hormone (GHRH) analog that stimulates the body's own GH output, FDA-approved for HIV-associated visceral fat accumulation.
Cognitive & Nootropic
Pillar →Cerebrolysin
A mixture of low-molecular-weight neuropeptides and amino acids derived from pig brain, used clinically in some countries for stroke and dementia.
Dihexa
An angiotensin-IV-derived compound studied in preclinical models for unusually potent synapse-forming (synaptogenic) activity.
P21
A peptidomimetic derived from a region of ciliary neurotrophic factor (CNTF), studied in animal models for neurogenesis and neuroprotection.
PE-22-28
A peptide derived from spadin, studied in animal models as a potential rapid-acting antidepressant through TREK-1 channel blockade.
Selank
A synthetic peptide derived from the immune fragment tuftsin, studied mainly in Russia for anxiolytic and mild cognitive effects.
Semax
A synthetic peptide derived from a fragment of ACTH, developed and used clinically in Russia and discussed for cognition and neuroprotection.
Longevity & Anti-Aging
Pillar →Epitalon
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied in longevity research, often in connection with the pineal peptide epithalamin and telomerase activity.
FOXO4-DRI
A designed peptide studied as a senolytic — selectively clearing senescent ('zombie') cells — with attention-getting animal results and no human data.
Humanin
A mitochondrial-derived peptide studied for cytoprotective, metabolic and neuroprotective effects, largely in preclinical models.
MOTS-c
A mitochondrial-derived peptide that acts as a metabolic signal, studied largely in animal models for effects on insulin sensitivity and exercise-like adaptations.
NAD+
A coenzyme central to cellular energy metabolism and DNA repair, discussed in the longevity space — though injectable NAD+ itself is not technically a peptide.
SS-31 (Elamipretide)
A mitochondria-targeting tetrapeptide that concentrates at the inner mitochondrial membrane and is in human trials for several mitochondrial and cardiac conditions.
Thymalin
A thymus-derived peptide preparation in the Khavinson 'bioregulator' tradition, studied mainly in Russia for immune modulation and aging-related outcomes.
Skin, Hair & Aesthetic
Pillar →AHK-Cu
A copper-binding cosmetic tripeptide, related to GHK-Cu but marketed primarily around hair appearance and follicle support.
Argireline (Acetyl Hexapeptide-8)
One of the most widely used topical cosmetic peptides, marketed to reduce the appearance of expression wrinkles.
GHK-Cu
A naturally occurring copper-binding tripeptide (Gly-His-Lys) with genuine topical cosmeceutical research and a wider base of anecdotal use for skin and hair.
Melanotan II
A melanocortin receptor agonist used unofficially for tanning and libido effects, with meaningful safety concerns and no approval for these uses.
PT-141
A melanocortin receptor agonist that acts on the nervous system rather than the vascular system; one formulation (bremelanotide / Vyleesi) is FDA-approved for a specific indication.
SNAP-8
A topical cosmetic peptide (an extension of the argireline concept) marketed to reduce the appearance of expression wrinkles.
Immune & Systemic
Pillar →LL-37
The body's principal cathelicidin antimicrobial peptide, central to host defense and studied for antimicrobial and wound-healing roles — with a notably double-edged biology.
Thymosin Alpha-1
An immune-modulating peptide naturally produced by the thymus; an approved drug (thymalfasin / Zadaxin) in a number of countries for specific clinical indications.
Thymosin Beta-4
A naturally occurring peptide central to cell migration and tissue repair — the parent molecule of the commonly discussed fragment TB-500.
Thymulin
A zinc-dependent thymic peptide involved in T-cell function, studied for immune-modulating and anti-inflammatory effects, largely preclinically.