Longevity & Anti-Aging
Longevity-adjacent peptides are discussed around mitochondrial function, cellular senescence and healthspan. Human longevity data is inherently hard to produce, so most evidence here is preclinical or early-stage.
Epitalon
MixedA synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied in longevity research, often in connection with the pineal peptide epithalamin and telomerase activity.
FOXO4-DRI
AnimalA designed peptide studied as a senolytic — selectively clearing senescent ('zombie') cells — with attention-getting animal results and no human data.
Humanin
AnimalA mitochondrial-derived peptide studied for cytoprotective, metabolic and neuroprotective effects, largely in preclinical models.
MOTS-c
AnimalA mitochondrial-derived peptide that acts as a metabolic signal, studied largely in animal models for effects on insulin sensitivity and exercise-like adaptations.
NAD+
MixedA coenzyme central to cellular energy metabolism and DNA repair, discussed in the longevity space — though injectable NAD+ itself is not technically a peptide.
SS-31 (Elamipretide)
HumanA mitochondria-targeting tetrapeptide that concentrates at the inner mitochondrial membrane and is in human trials for several mitochondrial and cardiac conditions.
Thymalin
MixedA thymus-derived peptide preparation in the Khavinson 'bioregulator' tradition, studied mainly in Russia for immune modulation and aging-related outcomes.