Growth Hormone Secretagogues
Growth hormone secretagogues are studied for their effect on the body’s own GH and IGF-1 release rather than supplying hormone directly. Evidence ranges from approved clinical agents to compounds with sparse human data.
CJC-1295
MixedA synthetic analog of growth hormone-releasing hormone (GHRH) designed for a longer duration of action, studied for stimulating the body's own GH release.
GHRP-2
HumanA growth-hormone-releasing peptide that stimulates GH via the ghrelin receptor, also increasing appetite.
GHRP-6
HumanAn early growth-hormone-releasing peptide acting on the ghrelin receptor, notable for pronounced appetite stimulation.
Hexarelin
HumanA potent growth-hormone-releasing peptide acting on the ghrelin receptor, with additional research interest in cardiac tissue.
IGF-1 LR3
AnimalA modified, long-acting analog of insulin-like growth factor 1 used as a research chemical for its anabolic signaling — with meaningful safety concerns.
Ipamorelin
MixedA selective ghrelin-receptor agonist studied as a growth hormone secretagogue — it prompts the pituitary to release the body's own growth hormone.
MK-677
MixedAn orally active ghrelin-receptor agonist (growth hormone secretagogue) that raises GH and IGF-1; a small molecule rather than a peptide, with some human study data.
Sermorelin
MixedA GHRH analog (the 1-29 fragment) with a history of approved diagnostic/clinical use, now commonly compounded as a growth hormone secretagogue.
Tesamorelin
HumanA stabilized growth-hormone-releasing hormone (GHRH) analog that stimulates the body's own GH output, FDA-approved for HIV-associated visceral fat accumulation.