GHRP-2
Also known as: growth hormone releasing peptide-2, pralmorelin
By GLPeptideSciences Editorial Team · How we evaluate evidence · Reviewed by Dr. George S. Watson, MD, Cardiothoracic Surgeon · Updated 2026-06-02
A growth-hormone-releasing peptide that stimulates GH via the ghrelin receptor, also increasing appetite.
What it is & how it works
What it is
GHRP-2 is a growth-hormone-releasing peptide that works through the ghrelin receptor to prompt the pituitary to release GH. It belongs to the same family as GHRP-6 and ipamorelin.
How it is thought to work
By activating the ghrelin receptor it triggers GH release and — as a side effect of that pathway — stimulates appetite. It’s often discussed alongside a GHRH like CJC-1295 for a combined effect.
The evidence and the caveat
There’s real human pharmacology here (it’s been used in GH-stimulation testing), but evidence for sustained body-composition or anti-aging benefit is limited, and it carries the GH-axis cautions.
What it's discussed & studied for
- Growth hormone / IGF-1 stimulation
- Appetite stimulation
Discussion of a use is not a claim that it works or is approved.
Research status
Has been used as a GH-stimulation test agent and studied in research settings; not approved as a general therapeutic. Often paired with a GHRH like CJC-1295.
Evidence quality
Real human pharmacology exists, but evidence for long-term body-composition or anti-aging use is limited.
Dosing discussion
Defined doses exist in research/diagnostic contexts; consumer protocols are extrapolated and unvalidated.
Educational summary of what is discussed in the literature and community — not a dosing recommendation or medical advice.
Safety & harm reduction
Raises GH/IGF-1 with the usual cautions (fluid retention, insulin sensitivity); also raises cortisol/prolactin somewhat. Stimulates hunger noticeably.
Sourcing literacy
No approved consumer product; research-market material is unverified.
Selected literature
FAQ
How is GHRP-2 different from ipamorelin?
Both act on the ghrelin receptor to stimulate GH, but GHRP-2 tends to raise appetite (and cortisol/prolactin) more, whereas ipamorelin is considered more selective.